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Skeletal structure of EGIS-7625.
Systematic (IUPAC) name
Clinical data
Legal status
  • UN: Unscheduled
CAS Number 755040-97-2
PubChem CID: 9930789
Chemical data
Formula C18H22N4O2
Molecular mass 326.17

EGIS-7625 (C18H22N4O2) is a selective and competitive 5-HT2B antagonist and synthetic organic compound.[1] It is experimentally proven to be directly associated with smooth stomach muscle construction of white rats in vivo, and variably effective in provoking a similar response in in vitro human stomach cells.[2] In high blood concentrations, it causes mild constriction of rabbit pulmonary arteries.[2]


  1. ^ CID 9930789 from PubChem
  2. ^ a b Kovács, Anikó; Gacsályi, Istvan; Wellmann, János; Schmidt, Éva; Szücs, Zsuzsanna; Dubreuil, Valérie; Nicolas, Jean Paul; Boutin, Jean; et al. (2003). "Effects of EGIS-7625, a Selective and Competitive 5-HT2B Receptor Antagonist". Cardiovascular Drugs and Therapy 17 (5/6): 427–34. doi:10.1023/B:CARD.0000015857.96371.43. PMID 15107597.