EGR3

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EGR3
Identifiers
Aliases EGR3, EGR-3, PILOT, early growth response 3
External IDs MGI: 1306780 HomoloGene: 37923 GeneCards: 1960
RNA expression pattern
PBB GE EGR3 206115 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001199880
NM_001199881
NM_004430

NM_001289925
NM_001289927
NM_018781

RefSeq (protein)

NP_001186809.1
NP_001186810.1
NP_004421.2

NP_061251.1

Location (UCSC) Chr 8: 22.69 – 22.69 Mb Chr 14: 70.08 – 70.08 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Early growth response protein 3 is a protein that in humans is encoded by the EGR3 gene.[1][2][3]

The gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controlling biological rhythm. It may also play a role in muscle development.[3]

References[edit]

  1. ^ Patwardhan S, Gashler A, Siegel MG, Chang LC, Joseph LJ, Shows TB, Le Beau MM, Sukhatme VP (Aug 1991). "EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors". Oncogene 6 (6): 917–28. PMID 1906159. 
  2. ^ Yang Y, Dong B, Mittelstadt PR, Xiao H, Ashwell JD (May 2002). "HIV Tat binds Egr proteins and enhances Egr-dependent transactivation of the Fas ligand promoter". J Biol Chem 277 (22): 19482–19487. doi:10.1074/jbc.M201687200. PMID 11909874. 
  3. ^ a b "Entrez Gene: EGR3 early growth response 3". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.