EIF2B5

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Eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols EIF2B5 ; CACH; CLE; EIF-2B; EIF2Bepsilon; LVWM
External IDs OMIM603945 MGI2446176 HomoloGene2903 GeneCards: EIF2B5 Gene
RNA expression pattern
PBB GE EIF2B5 212351 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 8893 224045
Ensembl ENSG00000145191 ENSMUSG00000003235
UniProt Q13144 Q8CHW4
RefSeq (mRNA) NM_003907 NM_172265
RefSeq (protein) NP_003898 NP_758469
Location (UCSC) Chr 3:
184.14 – 184.68 Mb
Chr 16:
20.5 – 20.51 Mb
PubMed search [1] [2]

Translation initiation factor eIF-2B subunit epsilon is a protein that in humans is encoded by the EIF2B5 gene.[1][2]


Interactions[edit]

EIF2B5 has been shown to interact with EIF2B2[3] and EIF2B1.[3][4]

References[edit]

  1. ^ Asuru AI, Mellor H, Thomas NS, Yu L, Chen JJ, Crosby JS, Hartson SD, Kimball SR, Jefferson LS, Matts RL (August 1996). "Cloning and characterization of cDNAs encoding the epsilon-subunit of eukaryotic initiation factor-2B from rabbit and human". Biochim Biophys Acta 1307 (3): 309–17. doi:10.1016/0167-4781(96)00054-1. PMID 8688466. 
  2. ^ "Entrez Gene: EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa". 
  3. ^ a b Anthony, T G; Fabian J R; Kimball S R; Jefferson L S (June 2000). "Identification of domains within the epsilon-subunit of the translation initiation factor eIF2B that are necessary for guanine nucleotide exchange activity and eIF2B holoprotein formation". Biochim. Biophys. Acta (NETHERLANDS) 1492 (1): 56–62. doi:10.1016/S0167-4781(00)00062-2. ISSN 0006-3002. PMID 10858531. 
  4. ^ Ewing, Rob M; Chu Peter, Elisma Fred, Li Hongyan, Taylor Paul, Climie Shane, McBroom-Cerajewski Linda, Robinson Mark D, O'Connor Liam, Li Michael, Taylor Rod, Dharsee Moyez, Ho Yuen, Heilbut Adrian, Moore Lynda, Zhang Shudong, Ornatsky Olga, Bukhman Yury V, Ethier Martin, Sheng Yinglun, Vasilescu Julian, Abu-Farha Mohamed, Lambert Jean-Philippe, Duewel Henry S, Stewart Ian I, Kuehl Bonnie, Hogue Kelly, Colwill Karen, Gladwish Katharine, Muskat Brenda, Kinach Robert, Adams Sally-Lin, Moran Michael F, Morin Gregg B, Topaloglou Thodoros, Figeys Daniel (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. (England) 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. 

Further reading[edit]