EIF3B

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EIF3B
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases EIF3B, EIF3-ETA, EIF3-P110, EIF3-P116, EIF3S9, PRT1, eukaryotic translation initiation factor 3 subunit B
External IDs MGI: 106478 HomoloGene: 2780 GeneCards: 8662
RNA expression pattern
PBB GE EIF3S9 203462 x at tn.png

PBB GE EIF3S9 208688 x at tn.png

PBB GE EIF3S9 211501 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001037283
NM_003751

NM_133916

RefSeq (protein)

NP_001032360.1
NP_003742.2

NP_598677.1

Location (UCSC) Chr 7: 2.35 – 2.38 Mb Chr 5: 140.42 – 140.44 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Eukaryotic translation initiation factor 3 subunit B is a protein that in humans is encoded by the EIF3B gene.[1][2]

Interactions[edit]

EIF3B has been shown to interact with P70-S6 Kinase 1[3] and EIF3A.[1][4][5][6]

See also[edit]

References[edit]

  1. ^ a b Méthot N, Rom E, Olsen H, Sonenberg N (February 1997). "The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170". J. Biol. Chem. 272 (2): 1110–6. doi:10.1074/jbc.272.2.1110. PMID 8995410. 
  2. ^ "Entrez Gene: EIF3S9 eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa". 
  3. ^ Holz MK, Ballif BA, Gygi SP, Blenis J (November 2005). "mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events". Cell 123 (4): 569–80. doi:10.1016/j.cell.2005.10.024. PMID 16286006. 
  4. ^ Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (October 2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3". Eur. J. Biochem. 270 (20): 4133–9. doi:10.1046/j.1432-1033.2003.03807.x. PMID 14519125. 
  5. ^ Harris TE, Chi A, Shabanowitz J, Hunt DF, Rhoads RE, Lawrence JC (April 2006). "mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin". EMBO J. 25 (8): 1659–68. doi:10.1038/sj.emboj.7601047. PMC 1440840. PMID 16541103. 
  6. ^ Block KL, Vornlocher HP, Hershey JW (November 1998). "Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3". J. Biol. Chem. 273 (48): 31901–8. doi:10.1074/jbc.273.48.31901. PMID 9822659. 

Further reading[edit]