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Protein EIF4E2 PDB 2jgb.png
Available structures
PDB Ortholog search: PDBe RCSB
Aliases EIF4E2, 4E-LP, 4EHP, EIF4EL3, IF4e, eukaryotic translation initiation factor 4E family member 2
External IDs MGI: 1914440 HomoloGene: 128466 GeneCards: EIF4E2
RNA expression pattern
PBB GE EIF4E2 213571 s at fs.png

PBB GE EIF4E2 209393 s at fs.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)


RefSeq (protein)
Location (UCSC) Chr 2: 232.55 – 232.58 Mb Chr 1: 87.21 – 87.24 Mb
PubMed search [1] [2]
View/Edit Human View/Edit Mouse

Eukaryotic translation initiation factor 4E type 2 is a protein that in humans is encoded by the EIF4E2 gene.[3][4][5] It belongs to the eukaryotic translation initiation factor 4E family.


EIF4E2 has been shown to interact with ARIH1.[6]


  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Mao M, Fu G, Wu JS, Zhang QH, Zhou J, Kan LX, Huang QH, He KL, Gu BW, Han ZG, Shen Y, Gu J, Yu YP, Xu SH, Wang YX, Chen SJ, Chen Z (Aug 1998). "Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 95 (14): 8175–80. doi:10.1073/pnas.95.14.8175. PMC 20949Freely accessible. PMID 9653160. 
  4. ^ Rom E, Kim HC, Gingras AC, Marcotrigiano J, Favre D, Olsen H, Burley SK, Sonenberg N (Jun 1998). "Cloning and characterization of 4EHP, a novel mammalian eIF4E-related cap-binding protein". J. Biol. Chem. 273 (21): 13104–9. doi:10.1074/jbc.273.21.13104. PMID 9582349. 
  5. ^ "Entrez Gene: EIF4E2 eukaryotic translation initiation factor 4E family member 2". 
  6. ^ Tan NG, Ardley HC, Scott GB, Rose SA, Markham AF, Robinson PA (Nov 2003). "Human homologue of ariadne promotes the ubiquitylation of translation initiation factor 4E homologous protein, 4EHP". FEBS Lett. 554 (3): 501–4. doi:10.1016/S0014-5793(03)01235-3. PMID 14623119. 

Further reading[edit]