EIF4E2

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EIF4E2
Protein EIF4E2 PDB 2jgb.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesEIF4E2, 4E-LP, 4EHP, EIF4EL3, IF4e, eukaryotic translation initiation factor 4E family member 2, h4EHP
External IDsMGI: 1914440 HomoloGene: 128466 GeneCards: EIF4E2
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for EIF4E2
Genomic location for EIF4E2
Band2q37.1Start232,550,674 bp[1]
End232,583,644 bp[1]
RNA expression pattern
PBB GE EIF4E2 213571 s at fs.png

PBB GE EIF4E2 209393 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001039169
NM_001039170
NM_023314
NM_001347083

RefSeq (protein)

NP_001034258
NP_001034259
NP_001334012
NP_075803

Location (UCSC)Chr 2: 232.55 – 232.58 MbChr 1: 87.21 – 87.24 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Eukaryotic translation initiation factor 4E type 2 is a protein that in humans is encoded by the EIF4E2 gene.[5][6][7] It belongs to the eukaryotic translation initiation factor 4E family.

Interactions[edit]

EIF4E2 has been shown to interact with ARIH1.[8]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000135930 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026254 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Mao M, Fu G, Wu JS, Zhang QH, Zhou J, Kan LX, Huang QH, He KL, Gu BW, Han ZG, Shen Y, Gu J, Yu YP, Xu SH, Wang YX, Chen SJ, Chen Z (Aug 1998). "Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 95 (14): 8175–80. doi:10.1073/pnas.95.14.8175. PMC 20949. PMID 9653160.
  6. ^ Rom E, Kim HC, Gingras AC, Marcotrigiano J, Favre D, Olsen H, Burley SK, Sonenberg N (Jun 1998). "Cloning and characterization of 4EHP, a novel mammalian eIF4E-related cap-binding protein". J. Biol. Chem. 273 (21): 13104–9. doi:10.1074/jbc.273.21.13104. PMID 9582349.
  7. ^ "Entrez Gene: EIF4E2 eukaryotic translation initiation factor 4E family member 2".
  8. ^ Tan NG, Ardley HC, Scott GB, Rose SA, Markham AF, Robinson PA (Nov 2003). "Human homologue of ariadne promotes the ubiquitylation of translation initiation factor 4E homologous protein, 4EHP". FEBS Lett. 554 (3): 501–4. doi:10.1016/S0014-5793(03)01235-3. PMID 14623119.

Further reading[edit]