ELAVL1

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ELAVL1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases ELAVL1, ELAV1, HUR, Hua, MelG, ELAV like RNA binding protein 1
External IDs MGI: 1100851 HomoloGene: 20367 GeneCards: ELAVL1
RNA expression pattern
PBB GE ELAVL1 201727 s at fs.png

PBB GE ELAVL1 201726 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001419

NM_010485

RefSeq (protein)

NP_001410

NP_034615.2
NP_034615

Location (UCSC) Chr 19: 7.96 – 8.01 Mb Chr 8: 4.29 – 4.33 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

ELAV-like protein 1 or HuR (human antigen R) is a protein that in humans is encoded by the ELAVL1 gene.[3][4]

The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. One of its best-known functions is to stabilize mRNAs in order to regulate gene expression.[5]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Ma WJ, Cheng S, Campbell C, Wright A, Furneaux H (Jun 1996). "Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein". J Biol Chem. 271 (14): 8144–8151. doi:10.1074/jbc.271.14.8144. PMID 8626503. 
  4. ^ Ma WJ, Furneaux H (Feb 1997). "Localization of the human HuR gene to chromosome 19p13.2". Hum Genet. 99 (1): 32–33. doi:10.1007/s004390050305. PMID 9003489. 
  5. ^ "Entrez Gene: ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.