ELAV-like protein 1

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Available structures
PDBOrtholog search: PDBe RCSB
AliasesELAVL1, ELAV1, HUR, Hua, MelG, ELAV like RNA binding protein 1
External IDsMGI: 1100851 HomoloGene: 20367 GeneCards: ELAVL1
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for ELAVL1
Genomic location for ELAVL1
Band19p13.2Start7,958,573 bp[1]
End8,005,659 bp[1]
RNA expression pattern
PBB GE ELAVL1 201727 s at fs.png

PBB GE ELAVL1 201726 at fs.png
More reference expression data
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC)Chr 19: 7.96 – 8.01 MbChr 8: 4.29 – 4.33 Mb
PubMed search[3][4]
View/Edit HumanView/Edit Mouse

ELAV-like protein 1 or HuR (human antigen R) is a protein that in humans is encoded by the ELAVL1 gene.[5][6]

The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. One of its best-known functions is to stabilize mRNAs in order to regulate gene expression.[7]

See also[edit]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000066044 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040028 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Ma WJ, Cheng S, Campbell C, Wright A, Furneaux H (Jun 1996). "Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein". J Biol Chem. 271 (14): 8144–8151. doi:10.1074/jbc.271.14.8144. PMID 8626503.
  6. ^ Ma WJ, Furneaux H (Feb 1997). "Localization of the human HuR gene to chromosome 19p13.2". Hum Genet. 99 (1): 32–33. doi:10.1007/s004390050305. PMID 9003489.
  7. ^ "Entrez Gene: ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)".

Further reading[edit]

This article incorporates text from the United States National Library of Medicine ([1]), which is in the public domain.