ELF2

ELF2
Identifiers
Aliases	ELF2, EU32, NERF, NERF-1A, NERF-1B, NERF-1a,b, NERF-2, E74 like ETS transcription factor 2
External IDs	MGI: 1916507; HomoloGene: 5006; GeneCards: ELF2; OMA:ELF2 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	139,177,218 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	51,248,084 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; epithelium of colon; ; ganglionic eminence; ; ventricular zone; ; muscle of thigh; ; Descending thoracic aorta; ; right lung; ; skin of thigh; ; skin of hip; ; ascending aorta;
	Top expressed in
	spermatocyte; ; spermatid; ; seminiferous tubule; ; ventricular zone; ; zygote; ; ganglionic eminence; ; dermis; ; Rostral migratory stream; ; tail of embryo; ; thymus;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; sequence-specific DNA binding; DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; cytosol; nuclear body; nucleoplasm;
Biological process	regulation of transcription by RNA polymerase II; positive regulation of transcription, DNA-templated; cell differentiation; negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; transcription, DNA-templated; regulation of B cell receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	1998
	69257
	ENSG00000109381
	ENSMUSG00000037174
	Q15723
	Q9JHC9
NM_001276457; NM_001276458; NM_001276459; NM_006874; NM_201999;
	NM_001331036
	NM_001291059; NM_001291062; NM_001291063; NM_023502; NM_001356358
NP_001263386; NP_001263387; NP_001263388; NP_001317965; NP_006865;
	NP_973728; NP_001358253; NP_001358265; NP_001358266; NP_001358267; NP_001358268
	NP_001277988; NP_001277991; NP_001277992; NP_075991; NP_001343287
	Wikidata
View/Edit Human	View/Edit Mouse

E74-like factor 2 (ELF2), formerly known as new Ets-related factor (NERF), is an ETS family transcription factor.^[5] In humans this protein is encoded by the ELF2 gene.^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000109381 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000037174 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Oettgen P, Akbarali Y, Boltax J, Best J, Kunsch C, Libermann TA (September 1996). "Characterization of NERF, a novel transcription factor related to the Ets factor ELF-1". Mol. Cell. Biol. 16 (9): 5091–106. PMC 231510. PMID 8756667.
^ "Entrez Gene: ELF2 E74-like factor 2 (ets domain transcription factor)".

References

Further reading