ELTD1

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
ADGRL4
Identifiers
AliasesADGRL4, ETL, KPG_003, ELTD1, adhesion G protein-coupled receptor L4
External IDsMGI: 2655562 HomoloGene: 11170 GeneCards: ADGRL4
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for ADGRL4
Genomic location for ADGRL4
Band1p31.1Start78,889,764 bp[1]
End79,006,718 bp[1]
RNA expression pattern
PBB GE ELTD1 219134 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_022159

NM_133222

RefSeq (protein)

NP_071442

NP_573485

Location (UCSC)Chr 1: 78.89 – 79.01 MbChr 3: 151.44 – 151.55 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

EGF, latrophilin and seven transmembrane domain-containing protein 1 is a latrophilin-like orphan receptor of the adhesion G protein-coupled receptor family. In humans this protein is encoded by the ELTD1 gene.[5][6] ELTD1 appears to have a role in angiogenesis, both physiological and pathological, as well as glioblastoma.[7]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000162618 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039167 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Nechiporuk T, Urness LD, Keating MT (May 2001). "ETL, a novel seven-transmembrane receptor that is developmentally regulated in the heart. ETL is a member of the secretin family and belongs to the epidermal growth factor-seven-transmembrane subfamily". J Biol Chem. 276 (6): 4150–4157. doi:10.1074/jbc.M004814200. PMID 11050079. 
  6. ^ "Entrez Gene: ELTD1 EGF, latrophilin and seven transmembrane domain containing 1". 
  7. ^ Dricu, Anica; Serban, Florentina; Artene, Stefan-Alexandru; Georgescu, Ada Maria; Purcaru, Stefana Oana; Tache, Daniela Elise; Alexandru, Oana (December 2015). "Epidermal growth factor, latrophilin, and seven transmembrane domain-containing protein 1 marker, a novel angiogenesis marker". OncoTargets and Therapy: 3767. doi:10.2147/OTT.S93843. 

Further reading[edit]