From Wikipedia, the free encyclopedia
  (Redirected from EMD-386,088)
Jump to: navigation, search
Systematic (IUPAC) name
CAS Registry Number 54635-62-0 YesY
ATC code None
PubChem CID: 10131112
Chemical data
Formula C14H14ClN2
Molecular mass 245.727 g/mol
 YesY (what is this?)  (verify)

EMD-386088 is an indole derivative which is used in scientific research. It acts as a potent and selective 5-HT6 receptor agonist, with a Ki of 1 nM, a significantly higher affinity than older 5-HT6 agonists such as EMDT, although it possesses moderate affinity for the 5-HT3 receptor as well.[1]

See also[edit]


  1. ^ Mattsson, C; Sonesson, C; Sandahl, A; Greiner, HE; Gassen, M; Plaschke, J; Leibrock, J; Böttcher, H (2005). "2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT6 receptor agonists". Bioorganic & Medicinal Chemistry Letters 15 (19): 4230–4. doi:10.1016/j.bmcl.2005.06.067. PMID 16055331.