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Echinoderm microtubule associated protein like 4
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols EML4 ; C2orf2; ELP120; EMAP-4; EMAPL4; ROPP120
External IDs OMIM607442 MGI1926048 HomoloGene56841 ChEMBL: 1075114 GeneCards: EML4 Gene
RNA expression pattern
PBB GE EML4 220386 s at tn.png
More reference expression data
Species Human Mouse
Entrez 27436 78798
Ensembl ENSG00000143924 ENSMUSG00000032624
UniProt Q9HC35 Q3UMY5
RefSeq (mRNA) NM_001145076 NM_001114361
RefSeq (protein) NP_001138548 NP_001107833
Location (UCSC) Chr 2:
42.17 – 42.33 Mb
Chr 17:
83.35 – 83.48 Mb
PubMed search [1] [2]

Echinoderm microtubule-associated protein-like 4 is a protein that in humans is encoded by the EML4 gene.[1]

This protein is involved in cancers when spliced with the anaplastic lymphoma kinase.[2]


  1. ^ "Entrez Gene: EML4 echinoderm microtubule associated protein like 4". 
  2. ^ Choi YL, Takeuchi K, Soda M, Inamura K, Togashi Y, Hatano S, Enomoto M, Hamada T, Haruta H, Watanabe H, Kurashina K, Hatanaka H, Ueno T, Takada S, Yamashita Y, Sugiyama Y, Ishikawa Y, Mano H (July 2008). "Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer". Cancer Res. 68 (13): 4971–6. doi:10.1158/0008-5472.CAN-07-6158. PMID 18593892. 

Further reading[edit]