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Dematin actin binding protein
Protein EPB49 PDB 1qzp.png
PDB rendering based on 1qzp.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols DMTN ; DMT; EPB49
External IDs OMIM125305 MGI99670 HomoloGene1496 GeneCards: DMTN Gene
RNA expression pattern
PBB GE EPB49 204505 s at tn.png
More reference expression data
Species Human Mouse
Entrez 2039 13829
Ensembl ENSG00000158856 ENSMUSG00000022099
UniProt Q08495 Q9WV69
RefSeq (mRNA) NM_001114135 NM_001252662
RefSeq (protein) NP_001107607 NP_001239591
Location (UCSC) Chr 8:
22.05 – 22.08 Mb
Chr 14:
70.6 – 70.64 Mb
PubMed search [1] [2]

Dematin is a protein that in humans is encoded by the EPB49 gene.[1][2][3]


  1. ^ Rana AP, Ruff P, Maalouf GJ, Speicher DW, Chishti AH (Aug 1993). "Cloning of human erythroid dematin reveals another member of the villin family". Proc Natl Acad Sci U S A 90 (14): 6651–5. doi:10.1073/pnas.90.14.6651. PMC 46990. PMID 8341682. 
  2. ^ Khanna R, Chang SH, Andrabi S, Azam M, Kim A, Rivera A, Brugnara C, Low PS, Liu SC, Chishti AH (May 2002). "Headpiece domain of dematin is required for the stability of the erythrocyte membrane". Proc Natl Acad Sci U S A 99 (10): 6637–42. doi:10.1073/pnas.052155999. PMC 124455. PMID 12011427. 
  3. ^ "Entrez Gene: EPB49 erythrocyte membrane protein band 4.9 (dematin)". 

Further reading[edit]