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Protein EPB49 PDB 1qzp.png
Available structures
PDB Ortholog search: PDBe RCSB
Aliases DMTN, DMT, EPB49, dematin actin binding protein
External IDs MGI: 99670 HomoloGene: 1496 GeneCards: DMTN
Gene location (Human)
Chromosome 8 (human)
Chr. Chromosome 8 (human)[1]
Chromosome 8 (human)
Genomic location for DMTN
Genomic location for DMTN
Band 8p21.3 Start 22,048,995 bp[1]
End 22,082,527 bp[1]
RNA expression pattern
PBB GE EPB49 204505 s at fs.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC) Chr 8: 22.05 – 22.08 Mb Chr 14: 70.6 – 70.64 Mb
PubMed search [3] [4]
View/Edit Human View/Edit Mouse

Dematin is a protein that in humans is encoded by the EPB49 gene.[5][6][7]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000158856 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022099 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Rana AP, Ruff P, Maalouf GJ, Speicher DW, Chishti AH (Aug 1993). "Cloning of human erythroid dematin reveals another member of the villin family". Proc Natl Acad Sci U S A. 90 (14): 6651–5. doi:10.1073/pnas.90.14.6651. PMC 46990Freely accessible. PMID 8341682. 
  6. ^ Khanna R, Chang SH, Andrabi S, Azam M, Kim A, Rivera A, Brugnara C, Low PS, Liu SC, Chishti AH (May 2002). "Headpiece domain of dematin is required for the stability of the erythrocyte membrane". Proc Natl Acad Sci U S A. 99 (10): 6637–42. doi:10.1073/pnas.052155999. PMC 124455Freely accessible. PMID 12011427. 
  7. ^ "Entrez Gene: EPB49 erythrocyte membrane protein band 4.9 (dematin)". 

Further reading[edit]