EPN2

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EPN2
Identifiers
Aliases EPN2, EHB21, epsin 2
External IDs MGI: 1333766 HomoloGene: 40710 GeneCards: EPN2
RNA expression pattern
PBB GE EPN2 203463 s at fs.png

PBB GE EPN2 203464 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_148921
NM_001102664
NM_014964

NM_001252188
NM_001252189
NM_010148

RefSeq (protein)

NP_001096134
NP_055779
NP_683723

NP_001239118.1
NP_034278.1
NP_001239117
NP_001239118
NP_034278

Location (UCSC) Chr 17: 19.22 – 19.34 Mb Chr 11: 61.52 – 61.58 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Epsin-2 is a protein that in humans is encoded by the EPN2 gene.[3][4]

This gene encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis. Alternate splicing of this gene results in two transcript variants encoding different isoforms.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Rosenthal JA, Chen H, Slepnev VI, Pellegrini L, Salcini AE, Di Fiore PP, De Camilli P (Dec 1999). "The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module". J Biol Chem. 274 (48): 33959–65. doi:10.1074/jbc.274.48.33959. PMID 10567358. 
  4. ^ a b "Entrez Gene: EPN2 epsin 2". 

Further reading[edit]