Since debuting in 1984, it has broadcast games from numerous conferences including the SEC, ACC, Big Ten and the Big East. In recent years, it has primarily featured the SEC as the second-choice game to CBS' national coverage earlier in the day. Games from the other conferences typically could air either on ESPN/ESPN2 or ABC, but the SEC does not offer such flexibility. This game is often seen as the ESPNGame of the Week along with the Thursday night telecast.
On August 30, 2008, the ESPN2 team of Mark Jones and Bob Davie commentated the Illinois-Missouri game. A week later (September 6, 2008), the ABC team of Brent Musburger and Kirk Herbstreit commentated the Miami–Florida game.
Ron Franklin worked the November 22, 2008 game with Ed Cunningham as they commentated the Florida State–Maryland game. This marked the first time since 2005 that Franklin called an ESPN College Football Saturday Primetime game.
On October 1, 2005, in a game that Ron Franklin was calling along with Bob Davie, sideline reporter Holly Rowe lauded Purdue defensive coordinator Brock Spack for using all three timeouts on defense despite trailing by four touchdowns late in the game. "If the coaches are giving up," Rowe added, "what does that say to the players?" Franklin responded: "Holly, it's not giving up. It's 49-21, sweetheart."
In response to that, Mo Davenport, senior coordinating producer for college football said, "It was an inappropriate comment, and we've communicated that to Ron. There's never a reason to say something so mean-spirited. Ron apologized. We dealt with it internally."
Many believe this was the cause for Franklin's demotion from the ESPN primetime game to the ESPN2 primetime game.