Parker was a native of Grosse Pointe, Michigan. She and Kerouac married in 1944. At the time, he was in jail as an accessory after the fact in Lucien Carr's murder of David Kammerer. This event expedited their intention to marry so that Edie could access an inheritance from her grandfather's then unprobated estate to post Kerouac's bail. The marriage was annulled in 1948.