Pace was extensively involved with the early development of The Catholic University of America. He was the first professor of psychology at CUA, and was the founding dean of its School of Philosophy. He held several administrative positions throughout his career, and was involved with many of the University's academic initiatives. He was one of the general editors of the edition of the Catholic Encyclopedia completed in 1914. In addition, Pace contributed to the founding of Trinity College, Washington, D.C.
In 1892 he became one of the first five psychologists elected to the American Psychological Association by its charter members. He was co-founder of the American Philosophical Association (1893), cofounder of the Catholic Philosophical Association (1926), co-founder and first editor of Catholic Educational Review (1911), cofounder and coeditor of the journal New Scholasticism (1926). Between 1907 and 1912 he was one of the leading editors of the fifteen-volume Catholic Encyclopedia. He was appointed by President Hoover to the National Advisory Committee on Education in 1926.