The Edward Dexter House is an historic house at 72 Waterman Street in the College Hill neighborhood of Providence, Rhode Island. It is a 2-1/2 story wood frame structure, built in 1795-97, with a hip roof topped by a square monitor. Its main facade is five bays wide, with the center bay flanked by two-story pilasters and topped by a small gable pediment. The well-preserved interior provided a template for an early-20th-century museum space designed by the Rhode Island School of Design to house a furniture collection donated by the house's then-owner, Charles Pendleton. The house is one of the few 18th-century houses in the city's College Hill neighborhood. It was originally located at the corner of George and Prospect Streets; in 1860 it was sawn in half and moved in sections to its present location.
The house was listed on the National Register of Historic Places in 1971.