Edward Rosen's academic life, including his education, was spent in New York. He graduated from the City College of New York in 1926 and he received his master's (1929) and doctoral degrees (1939) from Columbia University. He was a teacher at the City College of New York and the Graduate Center of the City University of New York until his retirement in 1977, with two interruptions: he was a visiting professor at the Massachusetts Institute of Technology in 1957–1958, and at Indiana University in 1963–1964. In 1983, six years after his retirement, he was appointed Distinguished Professor Emeritus at the City University of New York.
In the course his career, Edward Rosen published 11 books, more than 160 articles, and over 90 book reviews.
- Pfizer Award of the History of Science Society in 1968, for his translation of Kepler's Somnium.
- Medal from the Copernicus Society of America in 1973, for his many years of outstanding research and publication on the life and works of Nicholas Copernicus.
- Gold Order of Merit from the Polish People's Republic in 1978, for the same reason.
- Grant, Edward (March 1986). "Eloge: Edward Rosen, 12 December 1906–28 March 1985". Isis. 77 (1): 303–304. doi:10.1086/354044.
- Cohen, I. Bernard (May 1986). "Edward Rosen (1906–1985)". Journal for the History of Astronomy. 17 (49): 150–152. Bibcode:1986JHA....17..150C.
- Philip P. Wiener: Remembering Edward Rosen, in: Journal of the History of Ideas, Vol. 47, No. 1 (Jan. - Mar., 1986), pp. 159-161
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