Elephantopus scaber

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Elephantopus scaber
Elephantopus scaber in Narshapur forest, AP W2 IMG 0829.jpg
Elephantopus scaber in India
Scientific classification
E. scaber
Binomial name
Elephantopus scaber
  • Elephantopus carolinensis G.Mey.
  • Elephantopus sordidus Salisb.
  • Scabiosa cochinchinensis Lour.
  • Elephantopus plurisetus (O.Hoffm.) Clonts, syn of subsp. plurisetus
  • Elephantopus sinuatus Zoll. & Moritzi, syn of var. sinuatus
  • Asterocephalus cochinchinensis Sprengel

Elephantopus scaber is a tropical species of flowering plant in the sunflower family. It is native to tropical Africa, Eastern Asia, Indian Subcontinent, Southeast Asia, and northern Australia. It has become naturalized in tropical Africa and Latin America. Its natural habitat is subtropical or tropical moist montane forests.[2][3][4][5][6][7][8]


E. scaber is used as a traditional medicine.[9] Different parts of the plant are used in traditional medicine of India as an astringent agent, cardiac tonic, and diuretic, and is used for eczema, rheumatism, fever, and bladder stones.[10] E.scaber modulates inflammatory responses by inhibiting the production of TNFα and IL-1β.[11]

Chemical constituents[edit]

E. scaber contains elephantopin which is a germacranolide sesquiterpene lactone containing two lactone rings and an epoxide functional group.[12][13] 17,19-Dihydrodeoxyelephantopin, iso-17,19- dihydro-deoxy elephantopin and 8-hydroxyl naringenin are the most important bioactive compounds responsible for anti-bacterial activity.[citation needed] By UPLC MS Q-TOF, 34 components were identified.[11]

Subspecies and varieties[edit]

Varieties of E. scaber include:[1]

  • Elephantopus scaber subsp. plurisetus (O.Hoffm.) Philipson
  • Elephantopus scaber subsp. scaber
  • Elephantopus scaber var. scaber
  • Elephantopus scaber var. sinuatus (Mor.) Miq.


  1. ^ a b The Plant List, Elephantopus scaber L.
  2. ^ Flora of China, 地胆草 di dan cao Elephantopus scaber Linnaeus, Sp. Pl. 2: 814. 1753.
  3. ^ Atlas of Living Australia, Elephantopus scaber L.
  4. ^ Breedlove, D.E. 1986. Flora de Chiapas. Listados Florísticos de México 4: i–v, 1–246.
  5. ^ Humbert, H. 1960. Composées. Fl. Madagasc. 189: 198-199 description in French
  6. ^ Humbert, H. 1960. Composées. Fl. Madagasc. 189: plate I (1), figures 10-12 at right line drawings of Elephantopus scaber
  7. ^ Jeffrey, C. 1988. Notes on Compositae: V. The Vernonieae in East Tropical Africa. Kew Bulletin 43(2): 195–277.
  8. ^ Nelson, C. H. 2008. Catálogo de las Plantas Vasculares de Honduras 1–1576. Secretaria de Recursos Naturales y Ambiente, Tegucigalpa.
  9. ^ Poli, A; Nicolau, M; Simoes, Cm; Nicolau, Rm; Zanin, M (Aug 1992). "Preliminary pharmacologic evaluation of crude whole plant extracts of Elephantopus scaber. Part I: in vivo studies". Journal of Ethnopharmacology. 37 (1): 71–6. doi:10.1016/0378-8741(92)90005-C. ISSN 0378-8741. PMID 1453704.
  10. ^ Wang, Limei; Waltenberger, Birgit; Pferschy-Wenzig, Eva-Maria; Blunder, Martina; Liu, Xin; Malainer, Clemens; Blazevic, Tina; Schwaiger, Stefan; Rollinger, Judith M.; Heiss, Elke H.; Schuster, Daniela; Kopp, Brigitte; Bauer, Rudolf; Stuppner, Hermann; Dirsch, Verena M.; Atanasov, Atanas G. (2014). "Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): A review". Biochemical Pharmacology. 92 (1): 73–89. doi:10.1016/j.bcp.2014.07.018. PMC 4212005. PMID 25083916.
  11. ^ a b Abhimannue, Anu P.; Mohan, Mohind C.; B, Prakash Kumar (13 February 2016). "Inhibition of Tumor Necrosis Factor-α and Interleukin-1β Production in Lipopolysaccharide-Stimulated Monocytes by Methanolic Extract of Elephantopus scaber Linn and Identification of Bioactive Components". Applied Biochemistry and Biotechnology. 179 (3): 427–443. doi:10.1007/s12010-016-2004-0. PMID 26875087. S2CID 7097943.
  12. ^ "Antitumor activity of elephantopus scaber linn against dalton's ascitis lymphoma". Indian Journal of Pharmaceutical Sciences. 64 (1): 71–3. Jan–Feb 2002. Archived from the original on 2012-06-30.
  13. ^ "Elephantopus scaber". Germplasm Resources Information Network (GRIN). Agricultural Research Service (ARS), United States Department of Agriculture (USDA). Retrieved 7 May 2011.