Robins finished his medical training and residencies at Harvard, where he worked under biologically-oriented psychiatrist Mandel E. Cohen who would greatly influence his career and with whom he first developed ideas about operational definitions for psychiatric conditions (the theory of operationalization having been recently advanced by Harvard physicist and philosopher of science Percy Williams Bridgman). Robins rejected the then dominant psychoanalysis, having personally undergone it for a year as was the norm in training, describing it as 'silly' (he also had a relative who committed suicide at Harvard-affiliated McLean Hospital while being treated with psychoanalytic methods).
Move to St. Louis
Robins moved to the psychiatric department at Washington University in St. Louis in 1949, initially as a pharmacology fellow working in the lab of biochemist Oliver H. Lowry, author of the most cited scientific paper ever (on a method for measuring proteins).
In 1956/57 he conducted a large-scale community-based study of suicides in St Louis which involved detailed structured interviews with people who had been in regular contact with the person beforehand. This has been noted as the first completed example of a practice that was shortly thereafter termed psychological autopsy by researchers in Los Angeles (coiner Edwin S. Shneidman).
Robins became department head in 1963, despite having early signs of what would later be diagnosed as probable multiple sclerosis. He was married to Lee Robins, a sociologist associate of psychiatry at Washington.
Developing diagnostic criteria
Robins formed a close working trio with Samuel Guze and George Winokur, and from the late 1950s they developed criteria sets for a 'medical model of psychiatric disorders' Influential psychiatrist Gerald Klerman approvingly dubbed the approach "neo-Kraepelinian" in 1978. The trio were influenced by the classification system and diagnostic principles of German psychiatrist Emil Kraepelin, and more recently by a textbook Clinical Psychiatry by British psychiatrists, principally Willy Mayer-Gross who had previously worked in Germany at the same institute as Kraepelin.
Led by Robins, the trio published with several others in 1972 the so-called Feighner Criteria (named after the then junior psychiatrist John Feighner who was lead author on the paper, which would become the most cited in psychiatry). This led through into the Research Diagnostic Criteria developed with Robert Spitzer and others, which ultimately shaped the influential third edition of the Diagnostic and Statistical Manual of Mental Disorders published by the American Psychiatric Association. His wife Lee was also involved in the developments.
- The Making of DSM-III: A Diagnostic Manual's Conquest of American Psychiatry Hannah Decker, Oxford University Press, 13 June 2013. Chapter 3.
- A Tribute to Eli and Lee Robins - Citation Superstars. A Citationist Perspective on Biological Psychiatry Institute for Scientific Information, 1989
- Assessment and Prediction of Suicide Ronald W. Maris, American Association of Suicidology, Guilford Press, 1992. Chapter 8: Assessment in absentia. Pg 144.
- The Question of Suicide: 50 years of research on the mental health issue that was supposedly inscrutable By Jim Dryden, Washington Medical School Journal 'Outlook'.
- Training at Washington University School of Medicine in Psychiatry in the late 1950s, from the perspective of an affective disorder researcher. Clayton PJ., J Affect Disord. 2006 May;92(1):13-7. PMID 16527361