Emil Herman Grubbe (1 January 1875 — 26 March 1960) was probably the first American to use x-rays in the treatment of cancer. He was born in Chicago, and received his medical training at a homeopathic institute: the Hahnemann Medical College of Chicago. It was there that Grubbe assembled the first x-ray machine in Chicago in 1896, and that same year, used it to treat a woman with recurrent carcinoma of the breast. He assembled the machine and began to use it in treatments less than a year after Wilhelm Röntgen announced his discovery of the x-ray. By 1960, Grubbe had instructed over 7000 other doctors in the medical use of x-rays. In the course of his lifetime, he underwent more than 90 operations for multiple cancers caused by his intense, ongoing exposure to radiation, a disease from which he died. Honors were bestowed upon Grubbe by numerous institutions, including the American Cancer Society. He was also a fellow of the American College of Physicians. Grubbe left money in his will to the Chicago Radiological Society to fund the Grubbe Memorial Award.
- "Pioneer in X-Ray Therapy". Science. New Series. 125 (3236): 18–19. 4 January 1957. doi:10.1126/science.125.3236.18. JSTOR 1752791.
- Pendergrass, Eugene P. (Autumn 1965). "Review of The Life and Times of Emil H. Grubbe by Paul C. Hodges". Isis. 56 (3): 395. doi:10.1086/350038. JSTOR 228144.
- "Brief Biography of Emil Grubbe". Chicago Radiological Society. Retrieved 8 September 2011.
- "Emil H. Grubbe, M.D., F.A.C.P. (obituary)". British Medical Journal. 2 (5198): 609. 20 August 1960. doi:10.1136/bmj.2.5198.609-a. JSTOR 25392632.
- Evans, Titus C. (June 1951). "Review of X-Ray Treatment: Its Origin, Birth, and Early History by Emil Grubbe". Quarterly Review of Biology. 26 (2): 223. doi:10.1086/398163. JSTOR 2809298.
- Grubbe, Emil (1949). X-Ray Treatment: Its Origins, Birth, and Early History. St. Paul and Minneapolis, MN: Bruce Publishing Company.
- Hodges, Paul C. (1964). The Life and Times of Emil H. Grubbe. University of Chicago Press.
- Mukherjee, Siddhartha (16 November 2010). The Emperor of All Maladies: A Biography of Cancer. Simon and Schuster. ISBN 978-1-4391-0795-9. Retrieved 6 September 2011.
- "X-Ray Martyr". Time. 3 August 1959.