End organ damage

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search

End organ damage usually refers to damage occurring in major organs fed by the circulatory system (heart, kidneys, brain, eyes) which can sustain damage due to uncontrolled hypertension, hypotension, or hypovolemia.

Evidence of hypertensive damage[edit]

In the context of hypertension features include:[1]

Evidence of shock (poor end organ perfusion)[edit]

  • Kidney - poor urine output (less than 0.5 mL/kg), low glomerular filtration rate.
  • Skin - pallor or mottled appearance, capillary refill > 2 secs, cool limbs.
  • Brain - orientation to time, person, and place. The Glasgow Coma Scale may be used to quantify altered consciousness.


  1. ^ a b c d "CG34 Hypertension - quick reference guide" (PDF). National Institute for Health and Clinical Excellence. 28 June 2006. Archived from the original (PDF) on 2009-03-13. Retrieved 2009-03-04.