Enhydrocyon's dentition suggests this animal was a hypercarnivore or mesocarnivore. Species of Enhydrocyon were large, powerfully built carnivores with a short snout and deep jaws reminiscent of a jaguar. David Macdonald describes Enhydrocyon as a Canid-equivalent of a big cat-like carnivore.
†Enhydrocyon crassidens (24.4—22.7 Ma AEO). Type locality: Monroe Creek (American Museum of Natural History, Rosebud 12), Oglala Lakota County, South Dakota. Weight estimated to be 45-50 lbs. (Legendre & Roth).
†Enhydrocyon pahinsintewakpa (~24.5—23.3 Ma AEO). Type locality: Sharps SDSM V-5361 aka LACM 1983 (Sharps Formation), Oglala Lakota County, South Dakota. Weight was approximately 40-45 lbs. (John Alroy), (Legendre & Roth, S. Legendre and C. Roth. 1988. 
†Enhydrocyon sectorius (nomen vanum)
†Enhydrocyon stenocephalus (25.9—25.7 Ma (AEO). John Day Units G, H, I, and J., Wheeler County, Oregon. Weight 45-50 lbs. (Legendre & Roth).