Enterobacteria phage P4

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Enterobacteria phage P4
Virus classification
Group: Group I (dsDNA)
Order: Caudovirales
Family: Myoviridae
Genus: P2-like viruses
Species: Enterobacteria phage P4

Enterobacteria phage P4 (also known as satellite phage P4) is a temperate bacteriophage of the family Myoviridae.[1] It is a satellite virus, requiring P2-related helper phage to grow lytically.


The P4 virion has a tail and an icosohedral head containing a linear double-stranded DNA genome of 11,627 kb.[2][3]

Life cycle[edit]

Phage P4 infects Escherichia coli. It is a satellite virus which cannot engage in lytic growth without the presence of a P2-related helper phage. It generally follows a lysogenic life cycle: after infection, the P4 genome integrates into that of its host. The P4 genome can also exist on its own within the host cell and can replicate as a free plasmid.[4]


  1. ^ Pruss, G; Goldstein, RN; Calendar, R (June 1974). "In vitro packaging of satellite phage P4 DNA". Proceedings of the National Academy of Sciences of the United States of America. 71 (6): 2367–71. doi:10.1073/pnas.71.6.2367. PMC 388456Freely accessible. PMID 4526304. 
  2. ^ Briani, Federica; Dehò, Gianni; Forti, Francesca; Ghisotti, Daniela (2002). "The Plasmid Status of Satellite Bacteriophage P4". Plasmid. 45 (1): 1–17. doi:10.1006/plas.2000.1497. PMID 11319927. 
  3. ^ Claverie J-M, Abergel C (2009). "Mimivirus and its Virophage". Annual Review of Genetics. 43: 49–66. doi:10.1146/annurev-genet-102108-134255 – via Annual Reviews. (subscription required (help)). 
  4. ^ Christie, GE; Calendar, R (1990). "Interactions between satellite bacteriophage P4 and its helpers.". Annual Review of Genetics. 24: 465–90. doi:10.1146/annurev.ge.24.120190.002341. PMID 2088176. 

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