Eosinophilic ulcer of the oral mucosa

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Eosinophilic ulcer of the oral mucosa. H&E stain.

Eosinophilic ulcer of the oral mucosa (also known as eosinophilic ulcer of the tongue,[1] Riga–Fede disease,[1] and traumatic eosinophilic granuloma[1]) is a condition characterized by an ulcer with an indurated and elevated border.[2]:803 The lesion might be tender, fast-growing and the patient often not be aware of any trauma in the area.

Definition[edit]

Traumatic eosinophilic granuloma of the tongue (TEGT) is a reactive condition that commonly occurs on the ventral tongue.

Causes[edit]

It is often associated with trauma. However, other causes are suspected, such as drugs, inherent predisposition, immune reaction, or lymphoproliferative disorder.

Differential Diagnosis[edit]

Squamous Cell Carcinoma, Pyogenic granulomas, Lesions of a chronic granulomatous disease and Mesenchymal tumors

Treatment[edit]

When the lesion is excised, recurrence often occurs. Palliative care with nonsteroidal anti-inflammatory drugs (NSAIDs) may be used, and topical steroids can be curative. If the lesion does not respond to treatment, biopsy is required.

See also[edit]

References[edit]

  1. ^ a b c Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0. 
  2. ^ James, William D.; Berger, Timothy G. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0. 

3. Ficarra G, Prignano F, Romagnoli P. Traumatic eosinophilic granuloma of the oral mucosa: A lymphoproliferative disorder? Oral Oncol.1997;33(5):375-379.