Eosinophilic ulcer of the oral mucosa
Eosinophilic ulcer of the oral mucosa (also known as eosinophilic ulcer of the tongue, Riga–Fede disease, and traumatic eosinophilic granuloma) is a condition characterized by an ulcer with an indurated and elevated border.:803 The lesion might be tender, fast-growing and the patient often not be aware of any trauma in the area.
Traumatic eosinophilic granuloma of the tongue (TEGT) is a reactive condition that commonly occurs on the ventral tongue.
It is often associated with trauma. However, other causes are suspected, such as drugs, inherent predisposition, immune reaction, or lymphoproliferative disorder.
Squamous Cell Carcinoma, Pyogenic granulomas, Lesions of a chronic granulomatous disease and Mesenchymal tumors
When the lesion is excised, recurrence often occurs. Palliative care with nonsteroidal anti-inflammatory drugs (NSAIDs) may be used, and topical steroids can be curative. If the lesion does not respond to treatment, biopsy is required.
3. Ficarra G, Prignano F, Romagnoli P. Traumatic eosinophilic granuloma of the oral mucosa: A lymphoproliferative disorder? Oral Oncol.1997;33(5):375-379.