Epigen

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EPGN
Identifiers
Aliases EPGN, ALGV3072, EPG, PRO9904, epithelial mitogen
External IDs MGI: 1919170 HomoloGene: 19527 GeneCards: EPGN
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_053087

RefSeq (protein)

NP_001257918
NP_001257919
NP_001257920
NP_001257921
NP_001257922

NP_444317.1
NP_444317

Location (UCSC) Chr 4: 74.31 – 74.32 Mb Chr 5: 91.03 – 91.04 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Epigen also known as epithelial mitogen is a protein that in humans is encoded by the EPGN gene.[3][4]

Function[edit]

The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate.[3]

References[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.