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Clinical data
Legal status
  • US: DEA List I
CAS Number 511-08-0 YesY
PubChem CID 31116
ChemSpider 28873 N
Chemical data
Formula C35H39N5O5
Molar mass 609.714 g/mol
 NYesY (what is this?)  (verify)

Ergocristine is an ergopeptine and one of the ergot alkaloids. As of February 24, 2010 Ergocrisine has been federally scheduled. Because of the existing Controlled Substance Act regulatory controls on the LSD precursors lysergic acid, lysergic acid amide, ergotamine, and ergonovine, clandestine laboratory operators have sought uncontrolled sources of precursor material for the production of LSD. This has led to the illicit utilization of the precursor chemical ergocristine as a direct substitute for ergotamine and ergonovine for the illicit production of LSD. In fact, the largest clandestine LSD laboratory ever, William Leonard Pickard and Clyde Apperson, that was seized by the DEA utilized ergocristine as the LSD precursor. Recipes documenting procedures for utilizing ergocristine in LSD synthesis are easily found on the Internet.

The DEA determined that ergocristine was readily available from commercial chemical suppliers. DEA had identified at least three suppliers of ergocristine, of which one distributor is located domestically; the other two are based in Germany and the Czech Republic.[1][2]


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  2. ^ MICROGRAM BULLETIN, VOLUME 43, NUMBER 3, MARCH 2010, page 22.