Estradiol cypionate/testosterone enanthate

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Estradiol cypionate /
testosterone enanthate
Estradiol 17 beta-cypionate.svg
Testosterone enanthate.svg
Combination of
Estradiol cypionateEstrogen
Testosterone enanthateAndrogen; Anabolic steroid
Clinical data
Trade namesSupligol
Other namesEC/TE
Routes of
Intramuscular injection
CAS Number

Estradiol cypionate/testosterone enanthate (EC/TE), sold under the brand name Supligol, is an injectable combination medication of estradiol cypionate (EC), an estrogen, and testosterone enanthate (TE), an androgen/anabolic steroid, which is used in menopausal hormone therapy for women, to treat prostatic hypertrophy in men, to treat osteoporosis, and to suppress lactation in women, among other uses.[1][2] It contains 4 mg EC and 80 mg TE (57.5 mg free testosterone) in oil solution in each ampoule and is administered by intramuscular injection once every 3 to 6 weeks for hormone therapy in women.[1] The medication was marketed by 1976[1] and remains available today in Paraguay.[2]

Androgen replacement therapy formulations and dosages used in women
Route Medication Major brand names Form Dosage
Oral Testosterone undecanoate Andriol, Jatenzo Capsule 40–80 mg 1x/1–2 days
Methyltestosterone Metandren, Estratest Tablet 0.5–10 mg/day
Fluoxymesterone Halotestin Tablet 1–2.5 mg 1x/1–2 days
Normethandronea Ginecoside Tablet 5 mg/day
Tibolone Livial Tablet 1.25–2.5 mg/day
Prasterone (DHEA)b Tablet 10–100 mg/day
Sublingual Methyltestosterone Metandren Tablet 0.25 mg/day
Transdermal Testosterone Intrinsa Patch 150–300 μg/day
AndroGel Gel, cream 1–10 mg/day
Vaginal Prasterone (DHEA) Intrarosa Insert 6.5 mg/day
Injection Testosterone propionatea Testoviron Oil solution 25 mg 1x/1–2 weeks
Testosterone enanthate Delatestryl, Primodian Depot Oil solution 25–100 mg 1x/4–6 weeks
Testosterone cypionate Depo-Testosterone, Depo-Testadiol Oil solution 25–100 mg 1x/4–6 weeks
Testosterone isobutyratea Femandren M, Folivirin Aqueous suspension 25–50 mg 1x/4–6 weeks
Mixed testosterone esters Climacterona Oil solution 150 mg 1x/4–8 weeks
Omnadren, Sustanon Oil solution 50–100 mg 1x/4–6 weeks
Nandrolone decanoate Deca-Durabolin Oil solution 25–50 mg 1x/6–12 weeks
Prasterone enanthatea Gynodian Depot Oil solution 200 mg 1x/4–6 weeks
Implant Testosterone Testopel Pellet 50–100 mg 1x/3–6 months
Notes: Premenopausal women produce about 230 ± 70 μg testosterone per day (6.4 ± 2.0 mg testosterone per 4 weeks), with a range of 130 to 330 μg per day (3.6–9.2 mg per 4 weeks). Footnotes: a = Mostly discontinued or unavailable. b = Over-the-counter. Sources: See template.

See also[edit]


  1. ^ a b c Vademecum de bolsillo: guía de especialidades medicinales : con índice terapéutico actualizado (enfermedades y síntomas de urgencia). Editorial Celcius - J.J. Vallory. 1976. SUPLIGOL (Ampollas) Comp. Testosterona enantato 80 mg (-= Testosterona 57,5 mg) y Estradiol ciclopentil-propionato, 4 mg. — Indic. Climaterio y sus trastornos, hipertrofia de la próstata, osteoporosis, supresión de la lactancia, etc. — Doslf. Climaterio: 1 ampolla por via I.M. cada 3-6 semanas, segun el caso. Osteoporosis: 1 ampolla cada 3 semanas. Supresion de la lactancia: 1 ampolla despues del parto.
  2. ^ a b [1][dead link]