Estradiol furoate

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Estradiol furoate
Estradiol furoate.svg
Clinical data
Trade namesDi-Folliculine
Other namesEF; 17-Furoylestradiol; 17-(2-Furancarbonyl)estradiol
Routes of
Intramuscular injection
Drug classEstrogen; Estrogen ester
CAS Number
PubChem CID
Chemical and physical data
Molar mass366.457 g·mol−1
3D model (JSmol)

Estradiol furoate (EF), or estradiol 17β-furoate, sold under the brand name Di-Folliculine, is an estrogen medication and estrogen ester which is no longer marketed.[1] It is the C17β furoate ester of estradiol.[1] Estradiol benzoate has also been marketed under the brand name Di-Folliculine, and should not be confused with estradiol furoate.[2]

The duration of action of the related estradiol ester estradiol 3-furoate by intramuscular injection was studied in women in 1952.[3] Its duration in oil solution was found to be similar to that of estradiol benzoate in oil solution and shorter than that of estradiol dipropionate in oil solution.[3]

See also[edit]


  1. ^ a b J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 898. ISBN 978-1-4757-2085-3.
  2. ^ Pharmaceutical Abstracts. American Pharmaceutical Association. 1941. p. 149.
  3. ^ a b Ferin, J. (1952). "Relative duration of action of natural and synthetic estrogens administered parenterally in women with estrogen deficiency". The Journal of Clinical Endocrinology & Metabolism. 12 (1): 28–35. doi:10.1210/jcem-12-1-28. ISSN 0021-972X.