Estromustine

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Estromustine
Estromustine.svg
Clinical data
SynonymsEoM; Leo 271 f; Estrone 17β-3-N-bis(2-chloroethyl)carbamate; Estrone–cytostatic complex
Drug classChemotherapeutic agent; Estrogen; Estrogen ester
Pharmacokinetic data
Elimination half-life14 hours[1]
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC23H29Cl2NO3
Molar mass438.387 g/mol g·mol−1
3D model (JSmol)

Estromustine (developmental code name Leo 271 f), also known as estrone 17β-3-N-bis(2-chloroethyl)carbamate or estrone–cytostatic complex,[2] is a major active metabolite of the cystotatic antineoplastic agent and estrogen estramustine phosphate, a medication used in the treatment of prostate cancer.[1][3]

See also[edit]

References[edit]

  1. ^ a b Bruce A. Chabner; Dan L. Longo (7 December 2011). Cancer Chemotherapy and Biotherapy: Principles and Practice. Lippincott Williams & Wilkins. pp. 252–. ISBN 978-1-4511-4820-6.
  2. ^ http://repository.kulib.kyoto-u.ac.jp/dspace/handle/2433/122855
  3. ^ Medical Subject Headings: Supplementary chemical records. The Library. 1993. p. 684.