Estrone sulfate

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Estrone sulfate
Skeletal formula of estrone sulfate
Space-filling model of the estrone sulfate molecule
Names
IUPAC name
[(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate
Identifiers
438-67-5 YesY
ChEBI CHEBI:17474 YesY
ChEMBL ChEMBL494753 YesY
ChemSpider 2272513 YesY
DrugBank DB04574 YesY
4749
Jmol-3D images Image
PubChem 3001028
UNII 6K6FDA543A YesY
Properties
C18H22O5S
Molar mass 350.43 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Estrone sulfate is a sulfated estrone ester and estrogen found in the conjugated estrogen formulation Premarin.[1]

It has been described as a prognosis indicator for prostate cancer.[2]

See also[edit]

References[edit]

  1. ^ Horne C, Chew BP, Wiseman BS, Dziuk PJ (August 1983). "Relationship between the level of estrone sulfate in the plasma and the number of fetuses during pregnancy in the gilt". Biol. Reprod. 29 (1): 56–62. doi:10.1095/biolreprod29.1.56. PMID 6615969. 
  2. ^ Giton F, de la Taille A, Allory Y et al. (March 2008). "Estrone sulfate (E1S), a prognosis marker for tumor aggressiveness in prostate cancer (PCa)". J. Steroid Biochem. Mol. Biol. 109 (1–2): 158–67. doi:10.1016/j.jsbmb.2007.10.005. PMID 18337090.