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Combination of
EthambutolAnti-tuberculosis medication
IsoniazidAnti-tuberculosis medication
Clinical data
  • US: C (Risk not ruled out)
ATC code

Ethambutol/isoniazid is a medication used to treat tuberculosis.[1] It is a fixed dose combination of ethambutol and isoniazid.[1] It is used along with other antituberculosis medication.[1] It is taken by mouth.[1]

Side effects are those of the underlying medications.[1] More common side effects include poor coordination, numbness, and liver problems.[2] Liver problems may be severe and are more likely in people over the age of 50.[2] Use is not recommended in children.[1] It is unclear if use in pregnancy is safe for the baby.[2]

It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.[3] The wholesale cost in the developing world is about 1.47 to 1.99 USD a month.[4] The combination product is not available in Canada or the United States.[2]


  1. ^ a b c d e f WHO Model Formulary 2008 (PDF). World Health Organization. 2009. p. 140. ISBN 9789241547659. Archived (PDF) from the original on 13 December 2016. Retrieved 8 December 2016.
  2. ^ a b c d "Ethambutol and Isoniazid Drug Information, Professional". November 1998. Archived from the original on 21 December 2016. Retrieved 18 December 2016.
  3. ^ "WHO Model List of Essential Medicines (19th List)" (PDF). World Health Organization. April 2015. Archived (PDF) from the original on 13 December 2016. Retrieved 8 December 2016.
  4. ^ "Ethambutol + Isoniazid". International Drug Price Indicator Guide. Retrieved 8 December 2016.

Further reading[edit]