Ethyl carfluzepate

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Ethyl carfluzepate
Ethyl carfluzepate.svg
Systematic (IUPAC) name
Ethyl 7-chloro-5-(2-fluorophenyl)-1-(methylcarbamoyl)-2-oxo-3H-1,4-benzodiazepine-3-carboxylate
Identifiers
CAS Number 65400-85-3 N
PubChem CID 68856
ChemSpider 62089 YesY
UNII 36M73UIK01 N
Chemical data
Formula C20H17ClFN3O4
Molar mass 417.818
 NYesY (what is this?)  (verify)

Ethyl carfluzepate[1] is mainly a hypnotic drug which is a benzodiazepine derivative and induces sleep in a strong manner. It is similar to ethyl loflazepate in chemical structure, the other difference being an absence of methylcarbamoyl group. Its also similar in metabolism to this substance, only the methyl-carboxylate group would be the difference between the main metabolites. Two of the main metabolites must be the 3-hydroxylate or the substance with only a hydrogen atom at the 3-position of the molecule structure. In order to that the resulting main metabolite could probably be ethyl-7-cloro-5-(2-fluorophenyl)-1-methylcarbamate)-2-oxo-3H-1,4-benzodiazepine-3-hydroxylate (and the 3-OH instead of the 3H metabolite). Its properties are mainly sedative and hypnotic.[2][3]

References[edit]

  1. ^ DE 2719607 
  2. ^ "ethyl carfluzepate". psychotropics.dk. 2003. Retrieved 7 December 2009. 
  3. ^ "LIST OF INTERNATIONAL NON-PROPRIETARY NAMES (INNS), PROVIDED FOR PHARMACEUTICAL SUBSTANCES BY THE WORLD HEALTH ORGANIZATION, WHICH ARE FREE OF DUTY" (PDF). Official Journal of the European Communities. eur-lex.europa.eu. 23 October 2001. Retrieved 7 December 2009.