3D model (JSmol)
CompTox Dashboard (EPA)
|Molar mass||206.241 g·mol−1|
|Appearance||Colourless to pale yellow liquid|
|Melting point||7 to 8 °C (45 to 46 °F; 280 to 281 K)|
|Boiling point||272 to 275 °C (522 to 527 °F; 545 to 548 K)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|what is ?)(|
Because of its pleasant taste and aroma, ethyl methylphenylglycidate finds use in the fragrance industry, in artificial flavors, and in cosmetics. Its end applications include perfumes, soaps, beauty care products, detergents, pharmaceuticals, baked goods, candies, ice cream, and others.
Ethyl methylphenylglycidate is usually prepared by the condensation of acetophenone and the ethyl ester of monochloroacetic acid in the presence of a base, in a reaction known as the Darzens condensation.
Long-term, high-dose studies in rats have demonstrated that ethyl methylphenylglycidate has no significant adverse health effects and is not carcinogenic. The US Food and Drug Administration has classified ethyl methylphenylglycidate as generally recognized as safe (GRAS).
- Ethyl Methylphenylglycidate, chemicalland21.com
- David J. Rowe (2005). Chemistry and technology of flavors and fragrances. ISBN 0-8493-2372-X.
- Dunnington, D; Butterworth, MRS; Gaunt, IF; Mason, PL; Evans, JG; Gangolli, SD (1981). "Long-term toxicity study of ethyl methylphenylglycidate (strawberry aldehyde) in the rat". Food and Cosmetics Toxicology. 19 (6): 691–9. doi:10.1016/0015-6264(81)90522-8. PMID 7327470.
- "Food Additive Status List". Food and Drug Administration.