Ethylene bis(iodoacetate)

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Ethylene bis(iodoacetate)
Ethylene bis(iodoacetate).svg
Names
Preferred IUPAC name
Ethane-1,2-diyl bis(iodoacetate)
Other names
Ethane-1,2-diyl bis(2-iodoacetate)
S-10
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C6H8I2O4/c7-3-5(9)11-1-2-12-6(10)4-8/h1-4H2
    Key: KBCCFFGCRDUANG-UHFFFAOYSA-N
  • C(COC(=O)CI)OC(=O)CI
Properties
C6H8I2O4
Molar mass 397.935 g·mol−1
Hazards
Lethal dose or concentration (LD, LC):
16.1 mg/kg (mice, intraperitoneal)
4.94 mg/kg (dogs, intravenous)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Ethylene bis(iodoacetate), also known as S-10, is the iodoacetate ester of ethylene glycol. It's an alkylating agent that has been studied as an anticancer drug.[1]

See also[edit]

References[edit]

  1. ^ "Enzyme Alterable Alkylating Agents. VI. Synthesis, Chemical Properties, Toxicities, and Clinical Trial of Haloacetates and Haloacetamides Containing Enzyme-Susceptible Bonds". JNCI: Journal of the National Cancer Institute. August 1963. doi:10.1093/jnci/31.2.297.