Ethylestradiol

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Ethylestradiol
17-Ethylestradiol.svg
Clinical data
Synonyms17α-Ethylestradiol; 17α-Ethylestra-1,3,5(10)-triene-3,17β-diol
Drug classEstrogen
Identifiers
CAS Number
PubChem CID
ChEMBL
Chemical and physical data
FormulaC20H28O2
Molar mass300.442 g/mol g·mol−1
3D model (JSmol)

Ethylestradiol, or 17α-ethylestradiol, also known as 17α-ethylestra-1,3,5(10)-triene-3,17β-diol, is a synthetic estrogen which was never marketed. It occurs as an active metabolite of the anabolic steroids norethandrolone and ethylestrenol formed via aromatase and is believed to be responsible for the estrogenic effects of norethandrolone and ethylestrenol.[1] The 3-methyl ether of ethylestradiol has been used as an intermediate in the synthesis of certain 19-nortestosterone anabolic steroids.[2][3][4]

See also[edit]

References[edit]

  1. ^ William Llewellyn (2011). Anabolics. Molecular Nutrition Llc. pp. 330–, 591–598. ISBN 978-0-9828280-1-4.
  2. ^ Colton, Frank B.; Nysted, Leonard N.; Riegel, Byron; Raymond, Albert L (1957). "17-Alkyl-19-nortestosterones". Journal of the American Chemical Society. 79 (5): 1123–1127. doi:10.1021/ja01562a028. ISSN 0002-7863.
  3. ^ Fedorova, O. I.; Pekarskaya, E. S.; Lukashina, I. V.; Grinenko, G. S. (1974). "Synthesis of some derivatives op 19-nortestosterone from estra-1,3,5(10)-trienes". Pharmaceutical Chemistry Journal. 8 (8): 462–465. doi:10.1007/BF00757882. ISSN 0091-150X.
  4. ^ William Andrew Publishing (22 October 2013). Pharmaceutical Manufacturing Encyclopedia. Elsevier. pp. 1513–. ISBN 978-0-8155-1856-3.