^Published PCT application WO2012135589, "Methods of administering beta7 integrin antagonists," assigned to Genentech and Roche. Paragraph 146. For the FIB504 mAb, see Andrew DP et al. Distinct but overlapping epitopes are involved in alpha 4 beta 7-mediated adhesion to vascular cell adhesion molecule-1, mucosal addressin-1, fibronectin, and lymphocyte aggregation. J Immunol. 1994 Nov 1;153(9):3847-61. PMID7523506 as referenced in paragraph 146 of the PCT application.
^Makker J, Hommes DW. Etrolizumab for ulcerative colitis: the new kid on the block? Expert Opin Biol Ther. 2016 Apr;16(4):567-72. PMID26914639
^Rosenfeld G et al. Etrolizumab for induction of remission in ulcerative colitis. Cochrane Database Syst Rev. 2015 Dec 2;12:CD011661. PMID26630451