Briegel's family lived in Böblingen in 1978, when Eva was born. In 1982 they moved to Langgöns, Hessen, where Eva attended primary school, before moving to Linden where Eva attended the Anne-Frank-Schule. After spending one year at the Liebigschule in Gießen, Eva finally graduated from Gesamtschule Gießen-Ost. In her last year of school Eva sang in a number of bands and for different projects and showed a strong interest in a career in music. However, she started to study Art History in Heidelberg and dropped out after the first semester. She then spent a number of years studying various subjects at the Justus-Liebig-Universität Gießen but never graduated. During this time she had various part time jobs selling musical instruments and computers. Later she worked as waitress and barkeeper.
In 2000, Eva was asked by Goodwell Music to serve as a replacement singer for Miriam Adameit in the band Sunnyglade. She immediately agreed and became the new face of the band. In 2000, the band's name was changed to Juli (German for the month July). Although they originally sang songs with English lyrics, Juli returned to singing in their native language. Eva Briegel later said: "We didn't go back to German to find our identities, or anything – we just weren't good enough at English to express how we felt in our songs." The band has since released two successful albums, Es ist Juli (It's July, 2004) and Ein neuer Tag (A New Day, 2006), both of which reached multiple-platinum status.