Evocative/suppression testing

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Evocative/suppression testing
Medical diagnostics
OPS-301 code 1-797

Evocative/suppression testing refers to a class of tests performed where one substance is measured both before and after the administration of another substance to determine if the levels are stimulated ("evocative") or suppressed.[1]

They are most commonly performed in the evaluation of possible endocrine disorders.

Certain tests are performed in the evaluation of multiple conditions, and not all listed substances may be measured in each test.

Examples include:

Test name Substance administered Substance measured Condition evaluated
combined rapid anterior pituitary evaluation panel insulin, GnRH, TRH ACTH and cortisol, FSH, HGH, LH, prolactin, TSH hypopituitarism
TRH stimulation test TRH TSH secondary hypothyroidism
ACTH stimulation test ACTH cortisol, 17α-hydroxyprogesterone adrenal insufficiency, Congenital adrenal hyperplasia (21-hydroxylase, 3 beta)
metyrapone panel metyrapone cortisol, 11-deoxycortisol adrenal insufficiency
dexamethasone suppression test dexamethasone cortisol Cushing's syndrome
captopril suppression test captopril aldosterone primary aldosteronism
captopril challenge test captopril renin renal artery stenosis


  1. ^ Thomas Falen; Alice Noblin; Brandy Ziesemer (1 December 2010). Learning to Code with CPT/HCPCS 2011. Lippincott Williams & Wilkins. pp. 114–. ISBN 978-0-7817-8120-6. Retrieved 13 July 2011.