Extrinsic pathway

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In molecular biology, the term extrinsic pathway may refer to multiple cascades of protein interactions.

  • The extrinsic pathway of apoptosis refers to cell death induced by external factors that activate the death-inducing signaling complex.
  • The extrinsic pathway of blood coagulation is also known as the tissue factor pathway and refers to a cascade of enzymatic reactions resulting in blood clotting.