F20, F-20, F.XX, or F-XX may refer to:
- F20 manual transmission, a General Motors transmission
- Northrop F-20 Tigershark, a combat aircraft
- Farmall F-20, a model of Farmall tractor
- Fokker F.XX, a Dutch airliner
- Fujifilm FinePix F20, a digital camera
- HMS Gurkha (F20), a British ship
- Schizophrenia ICD-10 code
- BMW 1 Series (F20)
- A Honda F engine
- F/A-XX, an American development and acquisition program for a sixth-generation jet fighter
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