FARSA (gene)

From Wikipedia, the free encyclopedia
Jump to: navigation, search
FARSA
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases FARSA, CML33, FARSL, FARSLA, FRSA, PheHA, phenylalanyl-tRNA synthetase alpha subunit
External IDs MGI: 1913840 HomoloGene: 3280 GeneCards: FARSA
RNA expression pattern
PBB GE FARSA 216602 s at fs.png

PBB GE FARSA 202159 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004461

NM_025648

RefSeq (protein)

NP_004452

NP_079924.2
NP_079924

Location (UCSC) Chr 19: 12.92 – 12.93 Mb Chr 8: 84.86 – 84.87 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Phenylalanyl-tRNA synthetase alpha chain is an enzyme that in humans is encoded by the FARSA gene.[3][4]

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. This gene encodes a product which is similar to the catalytic subunit of prokaryotic and Saccharomyces cerevisiae phenylalanyl-tRNA synthetases (PheRS). This gene product has been shown to be expressed in a tumor-selective and cell cycle stage- and differentiation-dependent manner, the first member of the tRNA synthetase gene family shown to exhibit this type of regulated expression[4]

References[edit]

Further reading[edit]