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FAUC50

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File:Dopamine native-head FAUC50.png
FAUC50 derived covalent binding dopamine based dopamine agonist. cf. oxidopamine

FAUC50 is a template molecular skeletal super-structure that can have different joined native-head groups added to its chemical composition to make various biogenic amines, catecholamines and neurotransmitters of those aforementioned categories into covalent binding ligands.[1]

References

  1. ^ Weichert, D.; Kruse, A. C.; Manglik, A.; Hiller, C.; Zhang, C.; Hubner, H.; Kobilka, B. K.; Gmeiner, P. (2014). "Covalent agonists for studying G protein-coupled receptor activation". Proceedings of the National Academy of Sciences. 111 (29): 10744–10748. doi:10.1073/pnas.1410415111. ISSN 0027-8424. Full article.