FCGR3B

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FCGR3B
Protein FCGR3B PDB 1e4j.png
Available structures
PDB Human UniProt search: PDBe RCSB
Identifiers
Aliases FCGR3B, CD16, CD16b, FCG3, FCGR3, FCR-10, FCRIII, FCRIIIb, Fc fragment of IgG receptor IIIb
External IDs MGI: 2179523 HomoloGene: 477 GeneCards: 2215
RNA expression pattern
PBB GE FCGR3B 204006 s at tn.png

PBB GE FCGR3B 204007 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001271037
NM_000570
NM_001244753
NM_001271035
NM_001271036

NM_144559

RefSeq (protein)

NP_000561.3
NP_001231682.1
NP_001257964.1
NP_001257965.1
NP_001257966.1

n/a

Location (UCSC) Chr 1: 161.62 – 161.63 Mb Chr 1: 171.02 – 171.03 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

FCGR3B (Fc fragment of IgG, low affinity IIIb, receptor), also known as CD16b (Cluster of Differentiation 16b), is a human gene.[3]

Clinical relevance[edit]

Mutations and copy-number variations in this gene have been associated to clinical cases of glomerulonephritis.[4]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ "Entrez Gene: FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)". 
  4. ^ Aitman TJ, Dong R, Vyse TJ, Norsworthy PJ, Johnson MD, Smith J, Mangion J, Roberton-Lowe C, Marshall AJ, Petretto E, Hodges MD, Bhangal G, Patel SG, Sheehan-Rooney K, Duda M, Cook PR, Evans DJ, Domin J, Flint J, Boyle JJ, Pusey CD, Cook HT (Feb 2006). "Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans". Nature. 439 (7078): 851–5. doi:10.1038/nature04489. PMID 16482158. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.