FCGR3B

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
FCGR3B
Protein FCGR3B PDB 1e4j.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesFCGR3B, CD16, CD16b, FCG3, FCGR3, FCR-10, FCRIII, FCRIIIb, Fc fragment of IgG receptor IIIb, CD16A, FCGR3A
External IDsMGI: 2179523 HomoloGene: 477 GeneCards: FCGR3B
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for FCGR3B
Genomic location for FCGR3B
Band1q23.3Start161,623,196 bp[1]
End161,631,963 bp[1]
RNA expression pattern
PBB GE FCGR3B 204007 at fs.png

PBB GE FCGR3B 204006 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001271037
NM_000570
NM_001244753
NM_001271035
NM_001271036

NM_144559

RefSeq (protein)

NP_000561
NP_001231682
NP_001257964
NP_001257965
NP_001257966

NP_653142

Location (UCSC)Chr 1: 161.62 – 161.63 MbChr 1: 171.02 – 171.03 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

FCGR3B (Fc fragment of IgG, low affinity IIIb, receptor), also known as CD16b (Cluster of Differentiation 16b), is a human gene.[5]

Clinical relevance[edit]

Mutations and copy-number variations in this gene have been associated to clinical cases of glomerulonephritis.[6]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000162747 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000059089 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ "Entrez Gene: FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)". 
  6. ^ Aitman TJ, Dong R, Vyse TJ, Norsworthy PJ, Johnson MD, Smith J, Mangion J, Roberton-Lowe C, Marshall AJ, Petretto E, Hodges MD, Bhangal G, Patel SG, Sheehan-Rooney K, Duda M, Cook PR, Evans DJ, Domin J, Flint J, Boyle JJ, Pusey CD, Cook HT (Feb 2006). "Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans". Nature. 439 (7078): 851–5. doi:10.1038/nature04489. PMID 16482158. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.