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Fibroblast growth factor 14
Symbols FGF14 ; FGF-14; FHF-4; FHF4; SCA27
External IDs OMIM601515 MGI109189 HomoloGene3037 GeneCards: FGF14 Gene
Species Human Mouse
Entrez 2259 14169
Ensembl ENSG00000102466 ENSMUSG00000025551
UniProt Q92915 P70379
RefSeq (mRNA) NM_004115 NM_010201
RefSeq (protein) NP_004106 NP_034331
Location (UCSC) Chr 13:
101.71 – 102.4 Mb
Chr 14:
123.98 – 124.68 Mb
PubMed search [1] [2]

Fibroblast growth factor 14 is a protein that in humans is encoded by the FGF14 gene.[1][2][3]

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene.[3]


  1. ^ Smallwood PM, Munoz-Sanjuan I, Tong P, Macke JP, Hendry SH, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J (Oct 1996). "Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development". Proc Natl Acad Sci U S A 93 (18): 9850–7. doi:10.1073/pnas.93.18.9850. PMC 38518. PMID 8790420. 
  2. ^ Wozniak DF, Xiao M, Xu L, Yamada KA, Ornitz DM (Mar 2007). "Impaired spatial learning and defective theta burst induced LTP in mice lacking fibroblast growth factor 14". Neurobiol Dis 26 (1): 14–26. doi:10.1016/j.nbd.2006.11.014. PMC 2267915. PMID 17236779. 
  3. ^ a b "Entrez Gene: FGF14 fibroblast growth factor 14". 

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