FOSL2

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FOS-Like Antigen 2
Identifiers
Aliases FOSL2, Fos-Related Antigen, FRA-2, FRA2, FOS like 2, AP-1 trancription factor subunit
External IDs MGI: 102858 HomoloGene: 3845 GeneCards: 2355
RNA expression pattern
PBB GE FOSL2 205409 at tn.png

PBB GE FOSL2 218880 at tn.png

PBB GE FOSL2 218881 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005253

NM_008037

RefSeq (protein)

NP_005244.1

NP_032063.2

Location (UCSC) Chr 2: 28.39 – 28.42 Mb Chr 5: 32.14 – 32.16 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Fos-related antigen 2 (FRA2) is a protein that in humans is encoded by the FOSL2 gene.[3]

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.[3]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.