FOXN3

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FOXN3
Identifiers
AliasesFOXN3, C14orf116, CHES1, PRO1635, forkhead box N3
External IDsHomoloGene: 3809 GeneCards: FOXN3
Gene location (Human)
Chromosome 14 (human)
Chr.Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for FOXN3
Genomic location for FOXN3
Band14q31.3-q32.11Start89,124,871 bp[1]
End89,619,149 bp[1]
RNA expression pattern
PBB GE CHES1 205022 s at fs.png

PBB GE CHES1 205021 s at fs.png

PBB GE CHES1 218031 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005197
NM_001085471

n/a

RefSeq (protein)

NP_001078940
NP_005188

n/a

Location (UCSC)Chr 14: 89.12 – 89.62 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Forkhead box protein N3 is a protein that in humans is encoded by the FOXN3 gene.[3][4]

This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms.[4]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000053254 - Ensembl, May 2017
  2. ^ "Human PubMed Reference:".
  3. ^ Pati D, Keller C, Groudine M, Plon SE (Jun 1997). "Reconstitution of a MEC1-independent checkpoint in yeast by expression of a novel human fork head cDNA". Mol Cell Biol. 17 (6): 3037–46. PMC 232156. PMID 9154802.
  4. ^ a b "Entrez Gene: CHES1 checkpoint suppressor 1".

Further reading[edit]

External links[edit]