FREM2

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FREM2
Identifiers
Aliases FREM2
External IDs MGI: 2444465 HomoloGene: 18454 GeneCards: FREM2
RNA expression pattern
PBB GE FREM2 gnf1h02739 at fs.png

PBB GE FREM2 gnf1h07842 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_207361

NM_172862

RefSeq (protein)

NP_997244

NP_766450.2
NP_766450

Location (UCSC) Chr 13: 38.69 – 38.89 Mb Chr 3: 53.51 – 53.66 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

FRAS1-related extracellular matrix protein 2 is a protein that in humans is encoded by the FREM2 gene.[3][4]

This gene encodes a membrane protein that belongs to the FRAS1 family. This extracellular matrix protein is thought to be required for maintaining the integrity of the skin epithelium and the differentiated state of renal epithelia. The protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions during morphogenetic processes. Mutations in this gene are associated with Fraser syndrome.[4]

References[edit]

Further reading[edit]