FYB

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FYB
Protein FYB PDB 1ri9.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases FYB, ADAP, PRO0823, SLAP-130, SLAP130, FYN binding protein, THC3
External IDs MGI: 1346327 HomoloGene: 22664 GeneCards: FYB
RNA expression pattern
PBB GE FYB 205285 s at fs.png

PBB GE FYB 211795 s at fs.png

PBB GE FYB 211794 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001243093
NM_001465
NM_199335
NM_001349333

NM_001278269
NM_011815

RefSeq (protein)

NP_001230022
NP_001456
NP_955367
NP_001336262

NP_001265198.1
NP_035945.1
NP_001265198
NP_035945

Location (UCSC) Chr 5: 39.11 – 39.27 Mb Chr 15: 6.58 – 6.66 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

FYN binding protein (FYB-120/130), also known as FYB, ADAP (Adhesion- and Degranulation-promoting Adapter Protein), and SLAP-130 (SLP-76-associated phosphoprotein of 130 kDa) is a protein that in humans is encoded by the FYB gene.[3]

Interactions[edit]

FYB has been shown to interact with:

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ "Entrez Gene: FYB FYN binding protein (FYB-120/130)". 
  4. ^ da Silva AJ, Janssen O, Rudd CE (Dec 1993). "T cell receptor zeta/CD3-p59fyn(T)-associated p120/130 binds to the SH2 domain of p59fyn(T)". J. Exp. Med. 178 (6): 2107–13. doi:10.1084/jem.178.6.2107. PMC 2191307Freely accessible. PMID 7504057. 
  5. ^ a b Marie-Cardine A, Hendricks-Taylor LR, Boerth NJ, Zhao H, Schraven B, Koretzky GA (Oct 1998). "Molecular interaction between the Fyn-associated protein SKAP55 and the SLP-76-associated phosphoprotein SLAP-130". J. Biol. Chem. 273 (40): 25789–95. doi:10.1074/jbc.273.40.25789. PMID 9748251. 
  6. ^ Musci MA, Hendricks-Taylor LR, Motto DG, Paskind M, Kamens J, Turck CW, Koretzky GA. "Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases". J. Biol. Chem. 272 (18): 11674–7. doi:10.1074/jbc.272.18.11674. PMID 9115214. 
  7. ^ Liu J, Kang H, Raab M, da Silva AJ, Kraeft SK, Rudd CE (Jul 1998). "FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells". Proc. Natl. Acad. Sci. U.S.A. 95 (15): 8779–84. doi:10.1073/pnas.95.15.8779. PMC 21153Freely accessible. PMID 9671755. 

Further reading[edit]