FZD10

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FZD10
Identifiers
Aliases FZD10, CD350, FZ-10, Fz10, FzE7, hFz10, frizzled class receptor 10
External IDs MGI: 2136761 HomoloGene: 21411 GeneCards: 11211
RNA expression pattern
PBB GE FZD10 219764 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007197

NM_175284

RefSeq (protein)

NP_009128.1

NP_780493.1

Location (UCSC) Chr 12: 130.16 – 130.17 Mb Chr 5: 128.6 – 128.6 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Frizzled-10 is a protein that in humans is encoded by the FZD10 gene.[1][2] FZD10 has also been designated as CD350 (cluster of differentiation 350).

Function[edit]

This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.[2]

See also[edit]

References[edit]

  1. ^ Koike J, Takagi A, Miwa T, Hirai M, Terada M, Katoh M (Aug 1999). "Molecular cloning of Frizzled-10, a novel member of the Frizzled gene family". Biochemical and Biophysical Research Communications 262 (1): 39–43. doi:10.1006/bbrc.1999.1161. PMID 10448064. 
  2. ^ a b "Entrez Gene: FZD10 frizzled homolog 10 (Drosophila)". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.