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Frizzled class receptor 10
Symbols FZD10 ; CD350; FZ-10; Fz10; FzE7; hFz10
External IDs OMIM606147 MGI2136761 HomoloGene21411 IUPHAR: 238 GeneCards: FZD10 Gene
RNA expression pattern
PBB GE FZD10 219764 at tn.png
More reference expression data
Species Human Mouse
Entrez 11211 93897
Ensembl ENSG00000111432 ENSMUSG00000081683
UniProt Q9ULW2 Q8BKG4
RefSeq (mRNA) NM_007197 NM_175284
RefSeq (protein) NP_009128 NP_780493
Location (UCSC) Chr 12:
130.16 – 130.17 Mb
Chr 5:
128.6 – 128.6 Mb
PubMed search [1] [2]

Frizzled-10 is a protein that in humans is encoded by the FZD10 gene.[1][2] FZD10 has also been designated as CD350 (cluster of differentiation 350).

This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.[2]

See also[edit]


  1. ^ Koike J, Takagi A, Miwa T, Hirai M, Terada M, Katoh M (Sep 1999). "Molecular cloning of Frizzled-10, a novel member of the Frizzled gene family". Biochem Biophys Res Commun 262 (1): 39–43. doi:10.1006/bbrc.1999.1161. PMID 10448064. 
  2. ^ a b "Entrez Gene: FZD10 frizzled homolog 10 (Drosophila)". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.