FZD5

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FZD5
Identifiers
AliasesFZD5, C2orf31, HFZ5, frizzled class receptor 5
External IDsMGI: 108571 HomoloGene: 2590 GeneCards: FZD5
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for FZD5
Genomic location for FZD5
Band2q33.3Start207,762,598 bp[1]
End207,769,906 bp[1]
RNA expression pattern
PBB GE FZD5 206136 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_030804
NM_003468

NM_001033193
NM_001042659
NM_022721

RefSeq (protein)

NP_003459

NP_001036124
NP_073558

Location (UCSC)Chr 2: 207.76 – 207.77 MbChr 1: 64.73 – 64.74 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Frizzled-5 is a protein that in humans is encoded by the FZD5 gene.[5][6][7]

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.[7]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000163251 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000045005 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Wang Y, Macke JP, Abella BS, Andreasson K, Worley P, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J (Jun 1996). "A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled". J Biol Chem. 271 (8): 4468–76. doi:10.1074/jbc.271.8.4468. PMID 8626800.
  6. ^ Saitoh T, Hirai M, Katoh M (Jun 2001). "Molecular cloning and characterization of human Frizzled-5 gene on chromosome 2q33.3-q34 region". Int J Oncol. 19 (1): 105–10. doi:10.3892/ijo.19.1.105. PMID 11408929.
  7. ^ a b "Entrez Gene: FZD5 frizzled homolog 5 (Drosophila)".

Further reading[edit]

External links[edit]

  • "Frizzled Receptors: FZD5". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.