FZD5

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FZD5
Identifiers
Aliases FZD5, C2orf31, HFZ5, frizzled class receptor 5
External IDs MGI: 108571 HomoloGene: 2590 GeneCards: 7855
RNA expression pattern
PBB GE FZD5 206136 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_030804
NM_003468

NM_001033193
NM_001042659
NM_022721

RefSeq (protein)

NP_003459.2

NP_001036124.1
NP_073558.2

Location (UCSC) Chr 2: 207.76 – 207.77 Mb Chr 1: 64.73 – 64.74 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Frizzled-5 is a protein that in humans is encoded by the FZD5 gene.[1][2][3]

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.[3]

See also[edit]

References[edit]

  1. ^ Wang Y, Macke JP, Abella BS, Andreasson K, Worley P, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J (Jun 1996). "A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled". J Biol Chem 271 (8): 4468–76. doi:10.1074/jbc.271.8.4468. PMID 8626800. 
  2. ^ Saitoh T, Hirai M, Katoh M (Jun 2001). "Molecular cloning and characterization of human Frizzled-5 gene on chromosome 2q33.3-q34 region". Int J Oncol 19 (1): 105–10. doi:10.3892/ijo.19.1.105. PMID 11408929. 
  3. ^ a b "Entrez Gene: FZD5 frizzled homolog 5 (Drosophila)". 

External links[edit]

  • "Frizzled Receptors: FZD5". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.